Prostaglandin E1 is a commonly used topical drug for the treatment of erectile dysfunction.The mechanism of action of Alprostadil is mainly to penetrate the skin, penetrate the tunica albuginea, and enter the cavernous body, causing the smooth muscle of the penis to relax and expand the blood vessels, thereby increasing the blood supply of the cavernous body and improving erectile dysfunction. After prostaglandin E1 acts on the glans, it takes about 30 minutes to take
effect, and its overall effective rate is about 60%. Through prostaglandin E1, the blood supply to the cavernous body is improved,
and the purpose of treating male erectile dysfunction can be achieved. Because it is absorbed through the glans mucosa, the
clinical side effects are relatively small.
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1) Alprostadil is used in maintaining a patent ductus arteriosus in newborns.
2) Alprostadil powder is also as urethral suppositories and in injectable form.
3) Alprostadil is also used for critical limb ischemia.