|Place of Origin:||Shaanxi, China (Mainland)|
|Minimum Order Quantity:||10g|
|Packaging Details:||25kg carton drum (32cm*58cm)or 1kg foil bag (10cm*15cm) or by request of clients|
|Delivery Time:||1-3 work days|
|Payment Terms:||T/T, L/C, Western Union, MoneyGram|
|Supply Ability:||500kg per Month|
|Appearance:||White Powder||Grade:||Medicine Grade|
|Storage:||Cool And Dry||Shelf Life:||2 YEARS|
30123-17-2 Tianeptine Sodium Powder,
ISO9001 Tianeptine Sodium Powder,
|Product Name:||Tianeptine Powder|
|Grade Standard :||Pharmaceutical grade|
|Appearance:||Off- white to white powder|
Tianeptine sodium salt is a salt of Tianeptine. Tianeptine, a tricyclic compound, is a selective facilitator of 5-HT (serotonin; sc-201146) uptake in vitro and in vivo. Additionally, Tianeptine is reported to act as a selective inhibitor of dopamine uptake . Tianeptine does not have a noted effect on monoamine uptake. In a study utilizing purified synaptosomes from rat brain, Tianeptine was reported to enhance serotonin uptake in selective brain regions. Purified synaptosomes were obtained from rats and incubated with tritium-labeled 5-HT and Tianeptine in vitro . The synaptosomes were then analyzed for uptake and release of 5-HT via a liquid scintillation.
Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).
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